> ## Documentation Index > Fetch the complete documentation index at: https://docs.catalog.igvf.org/llms.txt > Use this file to discover all available pages before exploring further. # Genes Genes > Retrieve coexpressed gene pairs from CoXPresdb and genetic interactions from BioGRID. The following parameters can be used to set thresholds on z_score from CoXPresdb: gt (>), gte (>=), lt (\<), lte (\<=). At least one of these fields is required: gene_id, hgnc_id, gene_name, alias. The limit parameter controls the page size and can not exceed 100. Pagination is 0-based. **Examples by source** These examples are grouped by source; use the `source` filter to return data from a specific source. **BioGRID:** **Single result** - gene_id = ENSG00000112592 - associated_gene_id = ENSG00000163132 - source = BioGRID **Group results** - gene_id = ENSG00000112592 - source = BioGRID **COXPRESdb:** **Single result** - gene_id = ENSG00000153048 - associated_gene_id = ENSG00000233369 - source = COXPRESdb **Group results** - gene_id = ENSG00000153048 - source = COXPRESdb ## OpenAPI ````yaml /openapi/catalog-dev.openapi.json get /genes/genes openapi: 3.0.3 info: title: IGVF Catalog - Development description: >- Development IGVF Catalog OpenAPI compliant REST API built using tRPC with Express. Our database uses 0-based, half-open coordinates for genomic coordinates in the GRCh38 (human) and GRCm39 (mouse) reference genomes. Data is licensed under the Creative Commons license and the software is licensed under the MIT license. version: 1.2.0 - DEV servers: - url: https://catalog-api-dev.demo.igvf.org/api security: [] externalDocs: url: https://api-dev.catalog.igvf.org/openapi paths: /genes/genes: get: summary: Genes Genes description: >- Retrieve coexpressed gene pairs from CoXPresdb and genetic interactions from BioGRID. The following parameters can be used to set thresholds on z_score from CoXPresdb: gt (>), gte (>=), lt (\<), lte (\<=). At least one of these fields is required: gene_id, hgnc_id, gene_name, alias. The limit parameter controls the page size and can not exceed 100. Pagination is 0-based. **Examples by source** These examples are grouped by source; use the `source` filter to return data from a specific source. **BioGRID:** **Single result** - gene_id = ENSG00000112592 - associated_gene_id = ENSG00000163132 - source = BioGRID **Group results** - gene_id = ENSG00000112592 - source = BioGRID **COXPRESdb:** **Single result** - gene_id = ENSG00000153048 - associated_gene_id = ENSG00000233369 - source = COXPRESdb **Group results** - gene_id = ENSG00000153048 - source = COXPRESdb operationId: genesGenes parameters: - name: gene_id in: query required: false schema: type: string - name: hgnc_id in: query required: false schema: type: string - name: gene_name in: query required: false schema: type: string - name: alias in: query required: false schema: type: string - name: associated_gene_id in: query required: false schema: type: string - name: associated_hgnc_id in: query required: false schema: type: string - name: associated_gene_name in: query required: false schema: type: string - name: associated_alias in: query required: false schema: type: string - name: z_score in: query required: false schema: type: string - name: interaction_type in: query required: false schema: type: string enum: - dosage growth defect (sensu BioGRID) - dosage lethality (sensu BioGRID) - dosage rescue (sensu BioGRID) - negative genetic interaction (sensu BioGRID) - phenotypic enhancement (sensu BioGRID) - phenotypic suppression (sensu BioGRID) - positive genetic interaction (sensu BioGRID) - synthetic growth defect (sensu BioGRID) - synthetic lethality (sensu BioGRID) - synthetic rescue (sensu BioGRID) - name: label in: query required: false schema: type: string enum: - co-expression - genetic interference - name: method in: query required: false schema: type: string enum: - COXPRESdb - dosage growth defect (sensu BioGRID) - dosage lethality (sensu BioGRID) - >- dosage lethality (sensu BioGRID), phenotypic enhancement (sensu BioGRID) - >- dosage lethality (sensu BioGRID), synthetic lethality (sensu BioGRID) - dosage rescue (sensu BioGRID) - >- dosage rescue (sensu BioGRID), phenotypic enhancement (sensu BioGRID) - >- dosage rescue (sensu BioGRID), synthetic growth defect (sensu BioGRID) - negative genetic interaction (sensu BioGRID) - >- negative genetic interaction (sensu BioGRID), synthetic growth defect (sensu BioGRID) - >- negative genetic interaction (sensu BioGRID), synthetic lethality (sensu BioGRID) - >- negative genetic interaction (sensu BioGRID), synthetic lethality (sensu BioGRID), synthetic growth defect (sensu BioGRID) - phenotypic enhancement (sensu BioGRID) - >- phenotypic enhancement (sensu BioGRID), phenotypic suppression (sensu BioGRID) - >- phenotypic enhancement (sensu BioGRID), synthetic growth defect (sensu BioGRID) - >- phenotypic enhancement (sensu BioGRID), synthetic lethality (sensu BioGRID) - phenotypic suppression (sensu BioGRID) - >- phenotypic suppression (sensu BioGRID), negative genetic interaction (sensu BioGRID) - >- phenotypic suppression (sensu BioGRID), phenotypic enhancement (sensu BioGRID) - positive genetic interaction (sensu BioGRID) - >- positive genetic interaction (sensu BioGRID), negative genetic interaction (sensu BioGRID) - >- positive genetic interaction (sensu BioGRID), phenotypic enhancement (sensu BioGRID) - >- positive genetic interaction (sensu BioGRID), synthetic lethality (sensu BioGRID) - >- positive genetic interaction (sensu BioGRID), synthetic rescue (sensu BioGRID) - synthetic growth defect (sensu BioGRID) - >- synthetic growth defect (sensu BioGRID), phenotypic enhancement (sensu BioGRID) - synthetic haploinsufficiency (sensu BioGRID) - >- synthetic haploinsufficiency (sensu BioGRID), dosage rescue (sensu BioGRID) - >- synthetic haploinsufficiency (sensu BioGRID), phenotypic enhancement (sensu BioGRID), phenotypic suppression (sensu BioGRID) - synthetic lethality (sensu BioGRID) - >- synthetic lethality (sensu BioGRID), phenotypic enhancement (sensu BioGRID), phenotypic suppression (sensu BioGRID) - >- synthetic lethality (sensu BioGRID), synthetic growth defect (sensu BioGRID) - synthetic rescue (sensu BioGRID) - name: source in: query required: false schema: type: string enum: - BioGRID - COXPRESdb - name: name in: query required: false schema: type: string enum: - coexpressed with - interacts with - name: organism in: query required: false schema: type: string enum: - Mus musculus - Homo sapiens default: Homo sapiens - name: verbose in: query required: false schema: type: string enum: - 'true' - 'false' default: 'false' - name: page in: query required: false schema: type: number default: 0 - name: limit in: query required: false schema: type: number responses: '200': description: Successful response content: application/json: schema: type: array items: type: object properties: _id: type: string gene_1: anyOf: - type: string - type: array items: type: object properties: _id: type: string chr: type: string start: type: number nullable: true end: type: number nullable: true gene_type: type: string nullable: true name: type: string strand: type: string nullable: true hgnc: type: string nullable: true entrez: type: string nullable: true collections: type: array items: type: string nullable: true study_sets: type: array items: type: string nullable: true source: type: string version: type: string source_url: type: string required: - _id - chr - start - end - gene_type - name - source - version - source_url additionalProperties: false gene_2: anyOf: - type: string - type: array items: type: object properties: _id: type: string chr: type: string start: type: number nullable: true end: type: number nullable: true gene_type: type: string nullable: true name: type: string strand: type: string nullable: true hgnc: type: string nullable: true entrez: type: string nullable: true collections: type: array items: type: string nullable: true study_sets: type: array items: type: string nullable: true source: type: string version: type: string source_url: type: string required: - _id - chr - start - end - gene_type - name - source - version - source_url additionalProperties: false z_score: type: number detection_method: type: string detection_method_code: type: string interaction_type: type: array items: type: string interaction_type_code: type: array items: type: string confidence_value_biogrid: type: number nullable: true confidence_value_intact: type: number nullable: true pmids: type: array items: type: string label: type: string method: type: string class: type: string source: type: string source_url: type: string name: type: string required: - _id - gene_1 - gene_2 - label - method - class - source - name additionalProperties: false default: $ref: '#/components/responses/error' components: responses: error: description: Error response content: application/json: schema: type: object properties: message: type: string code: type: string issues: type: array items: type: object properties: message: type: string required: - message additionalProperties: false required: - message - code additionalProperties: false ````