> ## Documentation Index > Fetch the complete documentation index at: https://docs.catalog.igvf.org/llms.txt > Use this file to discover all available pages before exploring further. # Variants Phenotypes > Retrieve variant-trait pairs from GWAS, SGE, and cV2F by variants. Filters on phenotype ontology id can be used together. The following parameters can be used to set thresholds on -log10 p_value: gt (>), gte (>=), lt (\<), lte (\<=). Set verbose = true to retrieve full info on the studies. At least one of these fields is required: variant_id, spdi, hgvs, rsid, ca_id, region, method, or files_fileset. The limit parameter controls the page size and can not exceed 100. Pagination is 0-based. **Examples by method** These examples are grouped by method; use the `method` filter to return data from a specific method. **GWAS:** **query by variant identifier** - spdi = NC_000001.11:5277210:G:A - neg_log10_pvalue = gte:5 - method = GWAS **query by region** - region = chr1:5270008-5277214 - method = GWAS **SGE:** **query by variant identifier** - spdi = NC_000007.14:152660654:T:A - method = SGE **query by region** - region = chr7:152655654-152664654 - method = SGE **cV2F:** **query by variant identifier** - spdi = NC_000001.11:91420:T:C - method = cV2F **query by region** - region = chr1:91418-91424 - method = cV2F ## OpenAPI ````yaml /openapi/catalog-dev.openapi.json get /variants/phenotypes openapi: 3.0.3 info: title: IGVF Catalog - Development description: >- Development IGVF Catalog OpenAPI compliant REST API built using tRPC with Express. Our database uses 0-based, half-open coordinates for genomic coordinates in the GRCh38 (human) and GRCm39 (mouse) reference genomes. Data is licensed under the Creative Commons license and the software is licensed under the MIT license. version: 1.2.0 - DEV servers: - url: https://catalog-api-dev.demo.igvf.org/api security: [] externalDocs: url: https://api-dev.catalog.igvf.org/openapi paths: /variants/phenotypes: get: summary: Variants Phenotypes description: >- Retrieve variant-trait pairs from GWAS, SGE, and cV2F by variants. Filters on phenotype ontology id can be used together. The following parameters can be used to set thresholds on -log10 p_value: gt (>), gte (>=), lt (\<), lte (\<=). Set verbose = true to retrieve full info on the studies. At least one of these fields is required: variant_id, spdi, hgvs, rsid, ca_id, region, method, or files_fileset. The limit parameter controls the page size and can not exceed 100. Pagination is 0-based. **Examples by method** These examples are grouped by method; use the `method` filter to return data from a specific method. **GWAS:** **query by variant identifier** - spdi = NC_000001.11:5277210:G:A - neg_log10_pvalue = gte:5 - method = GWAS **query by region** - region = chr1:5270008-5277214 - method = GWAS **SGE:** **query by variant identifier** - spdi = NC_000007.14:152660654:T:A - method = SGE **query by region** - region = chr7:152655654-152664654 - method = SGE **cV2F:** **query by variant identifier** - spdi = NC_000001.11:91420:T:C - method = cV2F **query by region** - region = chr1:91418-91424 - method = cV2F operationId: phenotypesFromVariants parameters: - name: spdi in: query required: false schema: type: string - name: hgvs in: query required: false schema: type: string - name: rsid in: query required: false schema: type: string - name: ca_id in: query required: false schema: type: string - name: variant_id in: query required: false schema: type: string - name: region in: query required: false schema: type: string - name: phenotype_id in: query required: false schema: type: string - name: neg_log10_pvalue in: query required: false schema: type: string - name: method in: query required: false schema: type: string enum: - GWAS - SGE - cV2F - name: label in: query required: false schema: type: string enum: - GWAS - predicted variant effect on phenotype - protein variant effect - name: class in: query required: false schema: type: string enum: - observed data - prediction - name: organism in: query required: false schema: type: string enum: - Homo sapiens default: Homo sapiens - name: verbose in: query required: false schema: type: string enum: - 'true' - 'false' default: 'false' - name: page in: query required: false schema: type: number default: 0 - name: limit in: query required: false schema: type: number - name: files_fileset in: query required: false schema: type: string responses: '200': description: Successful response content: application/json: schema: type: array items: anyOf: - type: object properties: rsid: type: array items: type: string nullable: true phenotype_id: type: string nullable: true phenotype_term: type: string nullable: true study: anyOf: - type: string - type: object properties: _id: type: string name: type: string ancestry_initial: type: string nullable: true ancestry_replication: type: string nullable: true n_cases: type: string nullable: true n_initial: type: string nullable: true n_replication: type: string nullable: true pmid: type: string nullable: true pub_author: type: string nullable: true pub_date: type: string nullable: true pub_journal: type: string nullable: true pub_title: type: string nullable: true has_sumstats: type: string nullable: true num_assoc_loci: type: string nullable: true study_source: type: string nullable: true trait_reported: type: string nullable: true trait_efos: type: string nullable: true trait_category: type: string nullable: true source: type: string study_type: type: string nullable: true version: type: string nullable: true required: - _id - name - ancestry_initial - ancestry_replication - n_cases - n_initial - n_replication - pmid - pub_author - pub_date - pub_journal - pub_title - has_sumstats - num_assoc_loci - study_source - trait_reported - trait_efos - trait_category - study_type - version additionalProperties: false neg_log10_pvalue: type: number nullable: true p_value: type: number nullable: true beta: type: number nullable: true beta_ci_lower: type: number nullable: true beta_ci_upper: type: number nullable: true oddsr_ci_lower: type: number nullable: true oddsr_ci_upper: type: number nullable: true lead_chrom: type: string nullable: true lead_pos: type: number nullable: true lead_ref: type: string nullable: true lead_alt: type: string nullable: true direction: type: string nullable: true source: type: string default: OpenTargets source_url: type: string nullable: true class: type: string nullable: true method: type: string nullable: true label: type: string nullable: true version: type: string default: October 2022 (22.10) name: type: string variant: anyOf: - type: string - type: object properties: chr: type: string pos: type: number ref: type: string alt: type: string rsid: type: array items: type: string nullable: true spdi: type: string nullable: true hgvs: type: string nullable: true ca_id: type: string nullable: true _id: type: string required: - chr - pos - ref - alt additionalProperties: false required: - phenotype_id - phenotype_term - p_value - beta - beta_ci_lower - beta_ci_upper - oddsr_ci_lower - oddsr_ci_upper - lead_chrom - lead_pos - lead_ref - lead_alt - direction - name - variant additionalProperties: false - type: object properties: name: type: string biological_context: type: string nullable: true source: type: string source_url: type: string score: type: number nullable: true method: type: string nullable: true class: type: string nullable: true files_filesets: type: string nullable: true phenotype_term: type: string nullable: true variant: anyOf: - type: string - type: object properties: chr: type: string pos: type: number ref: type: string alt: type: string rsid: type: array items: type: string nullable: true spdi: type: string nullable: true hgvs: type: string nullable: true ca_id: type: string nullable: true _id: type: string required: - chr - pos - ref - alt additionalProperties: false phenotype_id: type: string nullable: true required: - name - source - source_url - score - method - files_filesets - phenotype_term - variant - phenotype_id additionalProperties: false default: $ref: '#/components/responses/error' components: responses: error: description: Error response content: application/json: schema: type: object properties: message: type: string code: type: string issues: type: array items: type: object properties: message: type: string required: - message additionalProperties: false required: - message - code additionalProperties: false ````