Proteins Proteins

curl --request GET \
  --url https://catalog-api-dev.demo.igvf.org/api/proteins/proteins

import requests

url = "https://catalog-api-dev.demo.igvf.org/api/proteins/proteins"

response = requests.get(url)

print(response.text)

const options = {method: 'GET'};

fetch('https://catalog-api-dev.demo.igvf.org/api/proteins/proteins', options)
  .then(res => res.json())
  .then(res => console.log(res))
  .catch(err => console.error(err));

[
  {
    "_id": "<string>",
    "protein_1": "<string>",
    "protein_2": "<string>",
    "detection_method": "<string>",
    "detection_method_code": "<string>",
    "interaction_type": [],
    "interaction_type_code": [
      "<string>"
    ],
    "confidence_value_biogrid": 123,
    "confidence_value_intact": 123,
    "label": "<string>",
    "class": "<string>",
    "method": "<string>",
    "source_url": "<string>",
    "source": "<string>",
    "organism": "<string>",
    "pmids": [
      "<string>"
    ],
    "name": "<string>"
  }
]

{
  "message": "<string>",
  "code": "<string>",
  "issues": [
    {
      "message": "<string>"
    }
  ]
}

API Reference

Proteins Proteins

Retrieve protein-protein interactions.

Set verbose = true to retrieve full info on the proteins.

Protein IDs support the following formats: ENSP00000384707.1 or ENSP00000384707 (Ensembl IDs) or P49711-2 (Uniprot ids)

Example: protein_id = ENSP00000384707.1,

protein_name = CTCF,

uniprot_name = CTCF_HUMAN,

uniprot_full_name = Transcriptional repressor CTCF,

dbxrefs = P49711,

detection_method = affinity chromatography technology,

interaction_type = physical association,

pmid = 28514442,

associated_protein_id = ENSP00000428899,

associated_protein_name = TNPO1,

associated_uniprot_name = TNPO1_HUMAN,

associated_uniprot_full_name = Transportin-1,

associated_dbxrefs = DIP-29335N,

label = affinity chromatography technology,

method = physical association,

source = BioGRID,

organism = Homo sapiens.

The limit parameter controls the page size and can not exceed 250.

Pagination is 0-based.

Proteins Proteins

curl --request GET \
  --url https://catalog-api-dev.demo.igvf.org/api/proteins/proteins

import requests

url = "https://catalog-api-dev.demo.igvf.org/api/proteins/proteins"

response = requests.get(url)

print(response.text)

const options = {method: 'GET'};

fetch('https://catalog-api-dev.demo.igvf.org/api/proteins/proteins', options)
  .then(res => res.json())
  .then(res => console.log(res))
  .catch(err => console.error(err));

[
  {
    "_id": "<string>",
    "protein_1": "<string>",
    "protein_2": "<string>",
    "detection_method": "<string>",
    "detection_method_code": "<string>",
    "interaction_type": [],
    "interaction_type_code": [
      "<string>"
    ],
    "confidence_value_biogrid": 123,
    "confidence_value_intact": 123,
    "label": "<string>",
    "class": "<string>",
    "method": "<string>",
    "source_url": "<string>",
    "source": "<string>",
    "organism": "<string>",
    "pmids": [
      "<string>"
    ],
    "name": "<string>"
  }
]

{
  "message": "<string>",
  "code": "<string>",
  "issues": [
    {
      "message": "<string>"
    }
  ]
}

Query Parameters

protein_id

string

protein_name

string

uniprot_name

string

uniprot_full_name

string

dbxrefs

string

associated_protein_id

string

associated_protein_name

string

associated_uniprot_name

string

associated_uniprot_full_name

string

associated_dbxrefs

string

pmid

string

detection_method

enum<string>

Available options:

3D electron microscopy,

Split renilla luciferase complementation,

acetylase assay,

adp ribosylase assay,

affinity chromatography technology,

affinity technology,

aggregation assay,

amplified luminescent proximity homogeneous assay,

ampylation assay,

anti bait coimmunoprecipitation,

anti tag coimmunoprecipitation,

antibody array,

array technology,

atomic force microscopy,

atpase assay,

avexis,

barcode fusion genetics two hybrid,

bead aggregation assay,

beta galactosidase complementation,

beta lactamase complementation,

bimolecular fluorescence complementation,

bio-layer interferometry,

biochemical,

bioluminescence resonance energy transfer,

biophysical,

biosensor,

blue native page,

chromatin immunoprecipitation array,

chromatin immunoprecipitation assay,

chromatography technology,

circular dichroism,

classical fluorescence spectroscopy,

cleavage assay,

coimmunoprecipitation,

comigration in gel electrophoresis,

comigration in non denaturing gel electrophoresis,

comigration in sds page,

competition binding,

confocal microscopy,

cosedimentation,

cosedimentation in solution,

cosedimentation through density gradient,

cross-linking study,

de-ADP-ribosylation assay,

deacetylase assay,

decarboxylation assay,

demethylase assay,

detection by mass spectrometry,

deubiquitinase assay,

differential scanning calorimetry,

dihydrofolate reductase reconstruction,

display technology,

dynamic light scattering,

electron diffraction,

electron microscopy,

electron microscopy 3D helical reconstruction,

electron microscopy 3D single particle reconstruction,

electron paramagnetic resonance,

electron tomography,

electrophoretic mobility shift assay,

electrophoretic mobility supershift assay,

electrophoretic mobility-based method,

enzymatic footprinting,

enzymatic study,

enzyme linked immunosorbent assay,

experimental interaction detection,

far western blotting,

field flow fractionation,

filamentous phage display,

filter binding,

filter trap assay,

fluorescence correlation spectroscopy,

fluorescence microscopy,

fluorescence polarization spectroscopy,

fluorescence recovery after photobleaching,

fluorescence technology,

fluorescence-activated cell sorting,

fluorescent resonance energy transfer,

footprinting,

force spectroscopy,

gal4 vp16 complementation,

gdp/gtp exchange assay,

glycosylase assay,

gtpase assay,

homogeneous time resolved fluorescence,

hydroxylase assay,

imaging technique,

immunodepleted coimmunoprecipitation,

in-gel kinase assay,

inference by socio-affinity scoring,

infrared spectroscopy,

interaction detection method,

interactome parallel affinity capture,

ion exchange chromatography,

ion mobility mass spectrometry of complexes,

isothermal titration calorimetry,

kinase homogeneous time resolved fluorescence,

kinase scintillation proximity assay,

lambda phage display,

lambda repressor two hybrid,

lex-a dimerization assay,

lexa b52 complementation,

lexa vp16 complementation,

light microscopy,

light scattering,

lipoprotein cleavage assay,

luminescence based mammalian interactome mapping,

mammalian protein protein interaction trap,

mass spectrometry studies of complexes,

mass spectrometry study of hydrogen/deuterium exchange,

methyltransferase assay,

methyltransferase radiometric assay,

microscale thermophoresis,

molecular sieving,

mrna display,

myristoylase assay,

neddylase assay,

nuclear magnetic resonance,

nuclease assay,

oxidase assay,

oxidoreductase assay,

p8 filamentous phage display,

palmitoylase assay,

peptide array,

phage display,

phosphatase assay,

phosphotransferase assay,

polymerization,

probe interaction assay,

protease accessibility laddering,

protease assay,

protein array,

protein complementation assay,

protein cross-linking with a bifunctional reagent,

protein kinase assay,

protein phosphatase assay,

protein three hybrid,

proteinchip(r) on a surface-enhanced laser desorption/ionization,

proximity labelling technology,

proximity ligation assay,

proximity-dependent biotin identification,

pull down,

reverse phase chromatography,

reverse ras recruitment system,

reverse two hybrid,

ribonuclease assay,

rna immunoprecipitation,

rna interference,

sandwich immunoassay,

saturation binding,

scanning electron microscopy,

scintillation proximity assay,

small angle neutron scattering,

solid phase assay,

solid state nmr,

solution state nmr,

split firefly luciferase complementation,

split luciferase complementation,

static light scattering,

sumoylase assay,

super-resolution microscopy,

surface plasmon resonance,

surface plasmon resonance array,

t7 phage display,

tandem affinity purification,

thermal shift binding,

three hybrid,

tox-r dimerization assay,

transcriptional complementation assay,

transmission electron microscopy,

two hybrid,

two hybrid array,

two hybrid bait and prey pooling approach,

two hybrid fragment pooling approach,

two hybrid pooling approach,

two hybrid prey pooling approach,

ubiquitin reconstruction,

ubiquitinase assay,

ultraviolet-visible spectroscopy,

unspecified method,

validated two hybrid,

virotrap,

x ray scattering,

x-ray crystallography,

x-ray fiber diffraction,

yeast display,

zymography

interaction_type

enum<string>

Available options:

acetylation reaction,

adp ribosylation reaction,

ampylation reaction,

association,

atpase reaction,

cleavage reaction,

colocalization,

covalent binding,

de-ADP-ribosylation reaction,

deacetylation reaction,

demethylation reaction,

deneddylation reaction,

dephosphorylation reaction,

deubiquitination reaction,

direct interaction,

disulfide bond,

dna cleavage,

enzymatic reaction,

glycosylation reaction,

gtpase reaction,

guanine nucleotide exchange factor reaction,

hydroxylation reaction,

lipid addition,

lipoprotein cleavage reaction,

methylation reaction,

myristoylation reaction,

neddylation reaction,

oxidoreductase activity electron transfer reaction,

palmitoylation reaction,

phosphorylation reaction,

phosphotransfer reaction,

physical association,

proline isomerization reaction,

protein cleavage,

proximity,

putative self interaction,

rna cleavage,

self interaction,

sumoylation reaction,

transglutamination reaction,

ubiquitination reaction

label

enum<string>

Available options:

3D electron microscopy,

Split renilla luciferase complementation,

acetylase assay,

adp ribosylase assay,

affinity chromatography technology,

affinity technology,

aggregation assay,

amplified luminescent proximity homogeneous assay,

ampylation assay,

anti bait coimmunoprecipitation,

anti tag coimmunoprecipitation,

antibody array,

array technology,

atomic force microscopy,

atpase assay,

avexis,

barcode fusion genetics two hybrid,

bead aggregation assay,

beta galactosidase complementation,

beta lactamase complementation,

bimolecular fluorescence complementation,

bio-layer interferometry,

biochemical,

bioluminescence resonance energy transfer,

biophysical,

biosensor,

blue native page,

chromatin immunoprecipitation array,

chromatin immunoprecipitation assay,

chromatography technology,

circular dichroism,

classical fluorescence spectroscopy,

cleavage assay,

coimmunoprecipitation,

comigration in gel electrophoresis,

comigration in non denaturing gel electrophoresis,

comigration in sds page,

competition binding,

confocal microscopy,

cosedimentation,

cosedimentation in solution,

cosedimentation through density gradient,

cross-linking study,

de-ADP-ribosylation assay,

deacetylase assay,

decarboxylation assay,

demethylase assay,

detection by mass spectrometry,

deubiquitinase assay,

differential scanning calorimetry,

dihydrofolate reductase reconstruction,

display technology,

dynamic light scattering,

electron diffraction,

electron microscopy,

electron microscopy 3D helical reconstruction,

electron microscopy 3D single particle reconstruction,

electron paramagnetic resonance,

electron tomography,

electrophoretic mobility shift assay,

electrophoretic mobility supershift assay,

electrophoretic mobility-based method,

enzymatic footprinting,

enzymatic study,

enzyme linked immunosorbent assay,

experimental interaction detection,

far western blotting,

field flow fractionation,

filamentous phage display,

filter binding,

filter trap assay,

fluorescence correlation spectroscopy,

fluorescence microscopy,

fluorescence polarization spectroscopy,

fluorescence recovery after photobleaching,

fluorescence technology,

fluorescence-activated cell sorting,

fluorescent resonance energy transfer,

footprinting,

force spectroscopy,

gal4 vp16 complementation,

gdp/gtp exchange assay,

glycosylase assay,

gtpase assay,

homogeneous time resolved fluorescence,

hydroxylase assay,

imaging technique,

immunodepleted coimmunoprecipitation,

in-gel kinase assay,

inference by socio-affinity scoring,

infrared spectroscopy,

interaction detection method,

interactome parallel affinity capture,

ion exchange chromatography,

ion mobility mass spectrometry of complexes,

isothermal titration calorimetry,

kinase homogeneous time resolved fluorescence,

kinase scintillation proximity assay,

lambda phage display,

lambda repressor two hybrid,

lex-a dimerization assay,

lexa b52 complementation,

lexa vp16 complementation,

light microscopy,

light scattering,

lipoprotein cleavage assay,

luminescence based mammalian interactome mapping,

mammalian protein protein interaction trap,

mass spectrometry studies of complexes,

mass spectrometry study of hydrogen/deuterium exchange,

methyltransferase assay,

methyltransferase radiometric assay,

microscale thermophoresis,

molecular sieving,

mrna display,

myristoylase assay,

neddylase assay,

nuclear magnetic resonance,

nuclease assay,

oxidase assay,

oxidoreductase assay,

p8 filamentous phage display,

palmitoylase assay,

peptide array,

phage display,

phosphatase assay,

phosphotransferase assay,

polymerization,

probe interaction assay,

protease accessibility laddering,

protease assay,

protein array,

protein complementation assay,

protein cross-linking with a bifunctional reagent,

protein kinase assay,

protein phosphatase assay,

protein three hybrid,

proteinchip(r) on a surface-enhanced laser desorption/ionization,

proximity labelling technology,

proximity ligation assay,

proximity-dependent biotin identification,

pull down,

reverse phase chromatography,

reverse ras recruitment system,

reverse two hybrid,

ribonuclease assay,

rna immunoprecipitation,

rna interference,

sandwich immunoassay,

saturation binding,

scanning electron microscopy,

scintillation proximity assay,

small angle neutron scattering,

solid phase assay,

solid state nmr,

solution state nmr,

split firefly luciferase complementation,

split luciferase complementation,

static light scattering,

sumoylase assay,

super-resolution microscopy,

surface plasmon resonance,

surface plasmon resonance array,

t7 phage display,

tandem affinity purification,

thermal shift binding,

three hybrid,

tox-r dimerization assay,

transcriptional complementation assay,

transmission electron microscopy,

two hybrid,

two hybrid array,

two hybrid bait and prey pooling approach,

two hybrid fragment pooling approach,

two hybrid pooling approach,

two hybrid prey pooling approach,

ubiquitin reconstruction,

ubiquitinase assay,

ultraviolet-visible spectroscopy,

unspecified method,

validated two hybrid,

virotrap,

x ray scattering,

x-ray crystallography,

x-ray fiber diffraction,

yeast display,

zymography

method

enum<string>

Available options:

acetylation reaction,

acetylation reaction, direct interaction,

adp ribosylation reaction,

adp ribosylation reaction, direct interaction,

adp ribosylation reaction, direct interaction, enzymatic reaction,

ampylation reaction,

association,

association, colocalization,

association, colocalization, direct interaction, physical association,

association, colocalization, physical association,

association, direct interaction,

association, direct interaction, physical association,

association, phosphorylation reaction,

association, physical association,

atpase reaction,

cleavage reaction,

cleavage reaction, direct interaction,

cleavage reaction, enzymatic reaction,

cleavage reaction, protein cleavage,

colocalization,

colocalization, direct interaction,

colocalization, direct interaction, physical association,

colocalization, physical association,

covalent binding,

covalent binding, association,

covalent binding, direct interaction,

de-ADP-ribosylation reaction,

deacetylation reaction,

deacetylation reaction, direct interaction,

demethylation reaction,

deneddylation reaction,

dephosphorylation reaction,

dephosphorylation reaction, direct interaction,

dephosphorylation reaction, physical association,

deubiquitination reaction,

direct interaction,

direct interaction, enzymatic reaction,

direct interaction, glycosylation reaction,

direct interaction, methylation reaction,

direct interaction, phosphorylation reaction,

direct interaction, physical association,

disulfide bond,

disulfide bond, association,

disulfide bond, direct interaction,

disulfide bond, physical association,

dna cleavage,

enzymatic reaction,

glycosylation reaction,

gtpase reaction,

guanine nucleotide exchange factor reaction,

hydroxylation reaction,

hydroxylation reaction, association,

lipoprotein cleavage reaction,

methylation reaction,

myristoylation reaction, lipid addition,

neddylation reaction,

neddylation reaction, direct interaction,

oxidoreductase activity electron transfer reaction,

palmitoylation reaction,

phosphorylation reaction,

phosphotransfer reaction,

physical association,

physical association, association,

physical association, colocalization,

physical association, direct interaction,

physical association, phosphorylation reaction,

proline isomerization reaction, direct interaction,

protein cleavage,

association, direct interaction, protein cleavage,

protein cleavage, direct interaction,

protein cleavage, phosphorylation reaction,

proximity,

direct interaction, proximity,

physical association, proximity,

putative self interaction,

rna cleavage,

self interaction,

physical association, self interaction,

sumoylation reaction,

direct interaction, sumoylation reaction,

transglutamination reaction,

ubiquitination reaction,

association, ubiquitination reaction,

direct interaction, ubiquitination reaction

source

enum<string>

Available options:

BioGRID,

BioGRID; IntAct,

IntAct

organism

enum<string>

default:Homo sapiens

Available options:

Mus musculus,

Homo sapiens

verbose

enum<string>

default:false

Available options:

true,

false

page

number

default:0

limit

number

Response

Successful response

_id

string

required

protein_1

required

protein_2

required

detection_method

string

required

detection_method_code

string

required

interaction_type

enum<string>[]

required

Available options:

acetylation reaction,

adp ribosylation reaction,

ampylation reaction,

association,

atpase reaction,

cleavage reaction,

colocalization,

covalent binding,

de-ADP-ribosylation reaction,

deacetylation reaction,

demethylation reaction,

deneddylation reaction,

dephosphorylation reaction,

deubiquitination reaction,

direct interaction,

disulfide bond,

dna cleavage,

enzymatic reaction,

glycosylation reaction,

gtpase reaction,

guanine nucleotide exchange factor reaction,

hydroxylation reaction,

lipid addition,

lipoprotein cleavage reaction,

methylation reaction,

myristoylation reaction,

neddylation reaction,

oxidoreductase activity electron transfer reaction,

palmitoylation reaction,

phosphorylation reaction,

phosphotransfer reaction,

physical association,

proline isomerization reaction,

protein cleavage,

proximity,

putative self interaction,

rna cleavage,

self interaction,

sumoylation reaction,

transglutamination reaction,

ubiquitination reaction

interaction_type_code

string[]

required

confidence_value_biogrid

number | null

required

confidence_value_intact

number | null

required

label

string

required

class

string

required

method

string

required

source_url

string

required

source

string

required

organism

string

required

pmids

string[]

required

name

string

required

Proteins Variants Proteins Complexes

Overview

Endpoints

Proteins Proteins

Query Parameters

Response