/region/[coordinates]/ancestry

The ancestry dashboard visualises gnomAD allele frequencies for every variant within the requested genomic interval.

Data Source

  • The page queries https://api.catalog.igvf.org/api/variants/gnomad-alleles?region={coordinates} and maps the response into population-specific frequency fields (AFR, AMI, AMR, ASJ, EAS, FIN, NFE, SAS).
  • Variants with a maximum allele frequency below the selected threshold are filtered out before any plots render.

Controls

  • Minimum Allele Frequency slider (0–0.20) filters the variant list; counts in the statistics card update in real time.
  • Bin Settings allow switching between fixed deciles (0–1, step 0.1) or dynamically computed bins for the per-population histograms.

Visualisations

  • The population distribution bar chart summarises how many variants carry non-zero frequency in each ancestry group.
  • Histograms for each population show the distribution of allele frequencies given the current filters and binning mode.
  • The heatmap ranks variants by how many populations keep them below 5% frequency, highlighting rare or population-specific signals so you can decide whether to pursue functional annotations elsewhere in the catalog.