/region/[coordinates]/ancestry
The ancestry dashboard visualises gnomAD allele frequencies for every variant within the requested genomic interval.
Data Source
- The page queries
https://api.catalog.igvf.org/api/variants/gnomad-alleles?region={coordinates}
and maps the response into population-specific frequency fields (AFR, AMI, AMR, ASJ, EAS, FIN, NFE, SAS). - Variants with a maximum allele frequency below the selected threshold are filtered out before any plots render.
Controls
- Minimum Allele Frequency slider (0–0.20) filters the variant list; counts in the statistics card update in real time.
- Bin Settings allow switching between fixed deciles (0–1, step 0.1) or dynamically computed bins for the per-population histograms.
Visualisations
- The population distribution bar chart summarises how many variants carry non-zero frequency in each ancestry group.
- Histograms for each population show the distribution of allele frequencies given the current filters and binning mode.
- The heatmap ranks variants by how many populations keep them below 5% frequency, highlighting rare or population-specific signals so you can decide whether to pursue functional annotations elsewhere in the catalog.